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once daily for 14 days) pretreatment and treatment alleviated the upregulation of S100A9 protein expression induced by 6-OHDA in C57BL/6 mice, as validated by immunofluorescence analysis

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(37898187) Buprenorphine’s antagonism of the kappa opioid receptor and mu opioid receptor may reduce opioid-related adverse effects (e.g., dysphoria, depression, and constipation)